Together we take ear
care to the next level

Animalcare are launching a unique 3-step approach which will offer a solution to first line ear problems and will give you confidence in managing them. With a range of 3 ear care products we will supply you with one complete solution for different kinds of ear problems. In this range you will find an ear cleaner (Oticare), ear drops (Aurimic) and a novel product that maintains a healthy ear canal which is based on powder (Oticurant).

Animalcare introduces: The Super-Earos!

Otitis externa, inflammation of the outer ear canal, represents one of the most common reasons that pets are presented at veterinary practices. (15-20%1, 2 in dogs and 2-6% in cats1)

There are many consequences of this condition; resulting in discomfort for pets as well as owners:

  • Odour
  • Scratching or rubbing of ears and head
  • Discharge in the ears
  • Redness or swelling of the ear flap or canal
  • Shaking of the head or tilting it to one side
  • Pain around the ears
  • Changes in behaviour such as depression or irritability

Pathogenesis

Primary causes of otitis externa directly cause inflammation. The major primary causes of otitis externa are: Allergy (atopy), parasites, foreign bodies, autoimmune disease and endocrine disorders (hypothyroidism/Cushings). More than 90% of chronic recurring otitis externa in dogs is due to atopic dermatitis or food intolerance4. In cats, one of the primary causes of inflammation is the ear mite, Otodectes cynotis.

Primary causes 5
Allergy Atopy, food, contact
Endocrine Hypothyroidism, hyperadrenocorticism
Autoimmune/immune-mediated P.foliaceus, bullous, pemphigoid, cutaneous (discoid) lupus erythematosus, erythema multiforme, vasculitis, drug eruption
Keratinisation disorders Sebaceous adenitis, primary idiopathic seborrhoea
Ectoparasites Otodectes cynotis, Demodex species
Foreign bodies Grass awns, sand (generally cause unilateral otitis)
Idiopathic Juvenile cellulitis

Secondary causes arise as a consequence of primary or predisposing conditions, exacerbating the otitis.

Opportunistic bacterial and yeast infections are the most common.

Staphylococcus (courtesy of Idexx)
Pseudomonas (courtesy of Idexx)
Malassezia (courtesy of Idexx)

Predisposing factors alter the ear environment making it more likely otitis will develop. Examples are conformation, neoplasia, environment and lifestyle (humidity/swimming).

Predisposing factors 5 Change
Conformation Hairy ears (e.g. Poodle), pendulous pinna (e.g. Basset), stenotic ear canals (e.g. Shar Pei), hairy concave pinna (e.g. Spaniels)
Excessive moisture Heat, humidity, water (swimmers’ ear, gundogs)
Obstructive ear disease Neoplasia, polyps, cysts
Systemic disease Renal, hepatic or pancreatic disease
Treatment effects Inappropriate cleaning solutions, traumatic cleaning, overuse of topical antimicrobials

Perpetuating factors prevent resolution and lead to relapse. These include inflammatory changes of the ear canal wall, hyperplasia of gland tissue and otitis media.

In the light of the widely divergent causes of otitis externa, a systematic diagnostic assessment is essential. The approach to ear disease is now that ear conditions are a specialised extension of the skin and otitis externa is now recognised as a dermatological condition6. Emphasis is placed on establishing a diagnosis through medical history, physical examination and cytological examination. Sometimes further work up is required such as culture and sensitivity testing, radiographs and biopsies.

History - Identification of the underlying cause.

The value of a complete history of a patient with otitis externa cannot be overemphasised 7. The ultimate goal is to define the primary problem or underlying cause of the recurrent otitis externa and getting a thorough history will aid in finding this primary problem.

Otoscopic examination

  • Ear mites can cause dry, dark, crumbly debris in the ear that resembles coffee granules.
  • Yeast can cause severe ear problems. We usually observe a brown waxy exudate and a sweet biscuit odour.
  • Bacterial ear infections can have a bad, metallic odour and often have a more yellowish exudate. A more purulent haemorrhagic discharge is seen with Pseudomonas.

Swabs of the ear can be taken for cytological analysis and examined for bacteria, yeast and mites.

  • A stained smear can quickly determine whether microbial overgrowth is present
  • Coccal organisms are usually Staphylococci or Streptococci
  • Rod-shaped organisms are usually Pseudomonas aeruginosa, Escherichia coli, or Proteus mirabilis. If they appear in large numbers this indicates that a bacterial culture with antibiotic sensitivity should be performed because of their known resistance to many antimicrobial agents

Blood work if necessary (for primary factors)

Management

The goals of management are to:

  • Resolve, remove, or control primary factors
  • Clean and dry the ear
  • Reduce inflammation
  • Resolve secondary infections

These goals are achieved through various cleaning techniques, topical and systemic therapies8. Topical therapy should be initiated as soon as possible to relieve inflammation. Prior to the administration of ear drops, it is advisable to first clean the ear canal with cleaning fluid in order to remove detritus and cerumen.

Treatment of otitis externa

Topical treatment

Most commercial topical products contain a combination of antibiotic, antifungal and glucocorticoid

  • Soothes clinical symptoms of inflammation
  • Alleviates pain and itching
  • Generally minimal systemic absorption

Systemical treatment

  • Aimed at the underlying cause
  • Pain management
  • Inflammation management – systemic corticosteroids
  • Antibiotic if necessary after susceptibility testing

The new range - the complete solution

These three products are easy to use and are incorporated in the 3 step approach which we will explain further in this section of the website.

3 easy steps

Oticare

Step 1:

Cleaning the pet's ears
with Oticare

Aurimic

Step 2:

Treating the pet's ears
with Aurimic

Brand New

Oticurant

Step 3:

Maintenance with Oticurant

Cleaning the pet’s ears with OTICARE

Oticare is a non-irritating ear cleaner specially formulated to keep dog’s and cat’s ears hygienically clean and maintain the normal microbiological flora of the ear canal. By removal of lipid substrates the necessary conditions for growth and reproduction of the organisms are eliminated. If the ear is not clean, topical medication cannot penetrate to the deeper parts of the ear where the discharge is thickest. Ceruminolytic cleaners should be administered to break up the wax and allow antibiotics to permeate the discharge.

Oticare contains

  • Lactic acid/natural lavender essential oil
    • Helps to maintain the microbial flora in the ear whilst calming the patient
  • Salicylic acid
    • Very effective cleaning and cerumen removal product (ceruminolytic)
    • Dead skin cell removal product (keratolytic)
    • Dries the skin
  • Docusate sodium
    • Effective ceruminolytic surfactant
    • Helps cleaning by emulsifying debris
  • Propylene glycol
    • Ceruminolytic
    • Helps with removal and elimination of wax and other fatty deposits

Key points:

  • Alcohol-free formulation
  • Calming & soothing essential oils
  • Very effective ceruminolytic – removes the cell debris and cerumen/wax
  • Low concentration of lactic acid and salicylic acid whilst still effective and gentle to the ear
  • Helps to maintain the normal flora in the ear canal
  • Easy to use
  • Pleasant fragrance
Ask your local representative about these easy-to-use and effective ear care products from the Super-earo’s Team.
Product code: XVD311

Treating the pet’s ears with AURIMIC

Aurimic provides a triple defence against otitis externa combining three tried and tested substances; polymyxin B, miconazole and prednisolone acetate. Aurimic is indicated for the treatment of otitis externa and small localised superficial skin infections in dogs and cats. Aurimic is also effective against ear mites, which can be a primary cause of otitis externa.

Miconazole has excellent efficacy against Malassezia yeast, targeting the cell wall and causing increased cell membrane permeability. Also, miconazole has been shown to possess antibacterial activity against gram-positive bacteria.

Polymyxin B, has anti-bacterial activity effects against gram-negative bacteria. At high concentrations, polymyxin B also interferes with the cell membranes of yeasts. At concentrations present in Aurimic when applied topically, polymyxin B shows virtually no systemic absorption (plasma levels are less than the limit of detection).

Polymyxin B and miconazole complement and potentiate one another effectively in their antimicrobial activity against the most important bacteria and yeasts involved in otitis externa, Staphylococcus pseudointermedius, Pseudomonas aeruginosa, Escherichia coli (among others) and Malassezia pachydermatis (among others) 9, 10.

Aurimic capitalises on this synergy, providing enhanced fungicidal and bactericidal activity. This synergy can help prevent resistance in fungal and bacterial pathogens.

Prednisolone, a corticosteroid, has rapid anti-inflammatory, anti-pruritic, anti-exudative and anti-proliferative effects and quickly alleviates the inflammation.

Usage Guidelines

Infections of the external auditory canal (otitis externa):

  1. Clean the external ear canal and place 5 drops into canal twice a day.
  2. Massage the ear and the canal gently to ensure proper distribution of the active substances.
  3. Treatment should be continued without interruption until a few days after complete disappearance of the clinical symptoms, at least for 7 - 10 days and up to 14 days.
  4. Where concurrent ear mite (Otodectes cynotis) infestation is present, consideration should be given to treating both ears even if infestation is only apparent in one ear. Instil 5 drops twice daily for 14 days.

Key points:

  • Combination of three tried and tested substances to treat the most common causes of otitis externa
  • Proven synergistic effects of polymyxin B and miconazole
  • Prednisolone - rapid anti-inflammatory and antipruritic effects without systemic absorption and side effects

See full summary of product characteristics on this website for more information.

Ask your local representative about these easy-to-use and effective ear care products from the Super-earo’s Team.

Product code: XVD310

Maintenance of healthy ears with OTICURANT

Oticurant is a novel ‘non-liquid’ concept in ear maintenance. It is an easy to administer odourless mixture of fine powders in single use sachets. The powders harmonise the environment in the ear canal, clean ears.

Staphylococcus and Malassezia overgrowth can occur in ears under the right conditions. These microorganisms are sensitive to changes in the physical environment in the ear. Lipids, moisture and a pH in the range of 5-8 are essential for the growth of yeast and bacteria. Therefore moisture, lipid levels and pH changes can significantly change optimal growth conditions and disturb colonisation. Malassezia will stop growing at pH ≤4 and Staphylococcus at pH <5.

Ingredients and their action:

  • Lactic acid
    • lowers pH (4)
    • limits ability of pathogens to grow
  • Kaolin and lactose
    • absorbs moisture and lipids
    • depletes the pathogens food supply to inhibit growth
    • cleans the ear
  • Special sugars (L-fucose, Human Milk Oligosaccharide and Bioecolia)
    • L-fucose and HMO prevent bacterial adherence by occupying lectins on the bacterial surface
    • Bioecolia limits colonisation of pathogenic or opportunistic bacteria
How does Oticurant clean ears and promote a healthy ear environment?
  • The powder forms small crystals when in contact with moisture
  • The crystals are the core of agglomerates consisting of moisture and fat
  • Agglomerates grow to different sizes depending on the amount of moisture and fat in the ear
  • When the agglomerates become sufficiently "heavy" they will be shaken out by the dog so are easily removed
  • Clean ears reduce the risk of ear problems
How do I use Oticurant?

First 5 days – one application per ear per day. To maintain balance in the ear canal – once per ear weekly as maintenance. .

How is Oticurant administered?
  1. Hold up the earflap and sprinkle the powder into the ear. Do not poke down the powder, just let it fall.
  2. Let go of the earflap
    • a portion of the powder can be shaken out which is normal and does not affect the result
    • there is no need to massage the ear
  3. Do the same procedure with the other ear

Key points:

  • Harmonises the ear environment
  • Lowers pH – limits ability of pathogens to grow
  • Cleans ears – depletes the pathogens food supply to inhibit growth
  • Cell decoy – smart sugars inhibit bacterial cell adhesion and the inflammatory process
  • No liquid in the ears – keep the environment dry
  • Cost effective easy to use ear maintenance product

Ask your local representative about these easy-to-use and effective ear care products from the Super-earo’s Team.

Product code: XVD312

Clinical Studies

Click here for a detailed list of the references used on this page.